Plasmids and the spread of antibiotic resistance
نویسندگان
چکیده
منابع مشابه
Antibiotic resistance plasmids spread among natural isolates of Escherichia coli in spite of CRISPR elements.
Clustered, regularly interspaced, short palindromic repeats (CRISPRs) are implicated in defence against foreign DNA in various archaeal and bacterial species. They have also been associated with a slower spread of antibiotic resistance. However, experimental and evolutionary studies raise doubts about the role of CRISPRs as a sort of immune system in Escherichia coli. We studied a collection of...
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Antibiotic resistance thwarts the treatment of infectious diseases worldwide. Although a number of factors can be identified which contribute to the problem, clearly the antibiotic as a selective agent and the resistance gene as the vehicle of resistance are the two most important, making up a 'drug resistance equation'. Both are needed in order for a clinical problem to arise. Given sufficient...
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As social interactions are increasingly recognized as important determinants of microbial fitness, sociobiology is being enlisted to better understand the evolution of clinically relevant microbes and, potentially, to influence their evolution to aid human health. Of special interest are situations in which there exists a "tragedy of the commons," where natural selection leads to a net reductio...
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ژورنال
عنوان ژورنال: The Biochemist
سال: 2015
ISSN: 0954-982X,1740-1194
DOI: 10.1042/bio03703012